On November 1, 2022, Dr. Zhang Fan's team from the Pancreatic Surgery Department of Binzhou Medical University Affiliated Hospital successfully carried out and completed an additional surgery for pancreatic tumors with the help of the High Voltage Pulse Minimally Invasive Therapeutic System independently developed and produced by Alpmed.

On October 9, 2022, Dr. Zhang Fan's team from the Pancreatic Surgery Department of Binzhou Medical University Affiliated Hospital in Shandong Province carried out an additional surgery for pancreatic tumors using the latest NanoKnife tumor ablation technology. With the guidance of CT puncture, they successfully completed the ablation treatment for a patient with malignant solid pancreatic tumor. The surgery used the High Voltage Steep Pulse Minimally Invasive Therapeutic System independently developed and produced by Shanghai Yuanshan Medical Technology Co., Ltd. (hereinafter referred to as "Alpmed").

Guangzhou Royal Lee Tumor Hospital is the largest high-end tertiary cancer specialty hospital in South China. The hospital pioneered the super-platform service model for cancer treatment, bringing together top cancer experts from domestic hospitals and equipped with the world's most advanced large-scale equipment such as PET-CT, MRI, and DSA. Recently, the hospital introduced the first Shanghai Yuanshan Medical independently developed and produced High Voltage Steep Pulse Minimally Invasive Therapeutic System in South China, bringing new minimally invasive treatment methods for complex solid tumor patients. On the morning of July 19, 2022, Professor Liu Haiying, honorary dean of Guangzhou Royal Lee Tumor Hospital and chief expert in oncology surgery, led a team to personally use this "domestic nano-knife" - Ailuoyi steep pulse minimally invasive treatment system. Through intraoperative ultrasound guidance, the team successfully performed a nano-knife surgery for a patient with liver cancer adjacent to the right portal vein.

After consultation, Dr. Deyu Li and his team from the Hepatobiliary and Pancreatic Surgery Department of Henan Provincial People's Hospital stated that the tumor was located in a special position, at the porta hepatis-pancreatic head space, adjacent to the celiac trunk and superior mesenteric artery, which posed a great challenge for surgery and conventional thermal ablation therapy. However, the Nanoknife ablation technology can be attempted as it can kill tumor cells, activate the body's immune system to engulf the remaining tumor cell fragments without damaging the pancreatic duct and surrounding large blood vessels. On March 15th, Dr. Li and his team successfully performed intraoperative Nanoknife ablation for the patient using the domestically produced Nanoknife system, the Steep Pulse Minimally Invasive Therapeutic System developed and produced by Shanghai Yuanshan Medical Technology Co., Ltd.

On April 13, under the leadership of Director Wan Chidan, Professor Xiong Jun successfully completed the laparoscopic ablation of the patient's Nanoknife. The operation was performed with the "Domestic Nanoknife", a steep pulse minimally invasive treatment system developed and manufactured by Shanghai Yuanshan Medical Technology Co.,Ltd.

On December 14, 2021, Professor Tang Zhe's team from the Department of General Surgery of the Fourth Hospital of Zhejiang University School of Medicine successfully completed a tumor ablation surgery for a 55-year-old female liver cancer patient through ultrasound-guided puncture using the innovative High Voltage Steep Pulse Minimally Invasive Therapeutic System developed by Shanghai Yuanshan Medical Technology Co.,Ltd (Alpmed)